3,677 research outputs found

    Boolean versus continuous dynamics on simple two-gene modules

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    We investigate the dynamical behavior of simple modules composed of two genes with two or three regulating connections. Continuous dynamics for mRNA and protein concentrations is compared to a Boolean model for gene activity. Using a generalized method, we study within a single framework different continuous models and different types of regulatory functions, and establish conditions under which the system can display stable oscillations. These conditions concern the time scales, the degree of cooperativity of the regulating interactions, and the signs of the interactions. Not all models that show oscillations under Boolean dynamics can have oscillations under continuous dynamics, and vice versa.Comment: 8 pages, 10 figure

    Relative Entropy of Coherent States on General CCR Algebras

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    For a subalgebra of a generic CCR algebra, we consider the relative entropy between a general (not necessarily pure) quasifree state and a coherent excitationthereof. We give a unified formula for this entropy in terms of single-particle modular data. Further, we investigate changes of the relative entropy along subalgebras arising from an increasing family of symplectic subspaces; here convexity of the entropy (as usually considered for the Quantum Null Energy Condition) is replaced with lower estimates for the second derivative, composed of “bulk terms” and “boundary terms”. Our main assumption is that the subspaces are in differential modular position, a regularity condition that generalizes the usual notion of half-sided modular inclusions. We illustrate our results in relevant examples, including thermal states for the conformal U(1)-current

    Classification of human actions into dynamics based primitives with application to drawing tasks

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    We develop the study of primitives of human motion, which we refer to as movemes. The idea is to understand human motion by decomposing it into a sequence of elementary building blocks that belong to a known alphabet of dynamical systems. How can we construct an alphabet of movemes from human data? In this paper we address this issue by introducing the notion of well-posednes. Using examples from human drawing data, we show that the well-posedness notion can be applied in practice so to establish if sets of actions, viewed as signals in time, can define movemes

    Practical Applications of Electromyography for Strength Coaches: A Case Study of the Isometric Squat

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    Longer Rest Intervals Attenuate Rate Pressure Product Response to Resistance Exercise in Untrained Young Women

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    Media use during adolescence: the recommendations of the Italian Pediatric Society.

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    BACKGROUND: The use of media device, such as smartphone and tablet, is currently increasing, especially among the youngest. Adolescents spend more and more time with their smartphones consulting social media, mainly Facebook, Instagram and Twitter because. Adolescents often feel the necessity to use a media device as a means to construct a social identity and express themselves. For some children, smartphone ownership starts even sooner as young as 7 yrs, according to internet safety experts. MATERIAL AND METHODS: We analyzed the evidence on media use and its consequences in adolescence. RESULTS: In literature, smartphones and tablets use may negatively influences the psychophysical development of the adolescent, such as learning, sleep and sigh. Moreover, obesity, distraction, addiction, cyberbullism and Hikikomori phenomena are described in adolescents who use media device too frequently. The Italian Pediatric Society provide action-oriented recommendations for families and clinicians to avoid negative outcomes. CONCLUSIONS: Both parents and clinicians should be aware of the widespread phenomenon of media device use among adolescents and try to avoid psychophysical consequences on the youngest

    Hydration Status Effect on Anaerobic Power and Fatigue in Collegiate Female Soccer Players

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    Surface EMG crosstalk quantified at the motor unit population level for muscles of the hand, thigh, and calf

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    Crosstalk is an important source of error in interpreting surface electromyography (EMG) signals. Here, we aimed at characterizing crosstalk for three groups of synergistic muscles by the identification of individual motor unit action potentials. Moreover, we explored whether spatial filtering (single and double differential) of the EMG signals influences the level of crosstalk. Three experiments were conducted. Participants (total twenty-five) performed isometric contractions at 10% of the maximal voluntary contraction (MVC) with digit muscles and knee extensors, and at 30% MVC with plantar flexors. High-density surface EMG signals were recorded and decomposed into motor unit spike trains. For each muscle, we quantified the crosstalk induced to neighboring muscles and the level of contamination by the nearby muscle activity. We also estimated the influence of crosstalk on the EMG power spectrum and intermuscular correlation. Most motor units (80%) generated significant crosstalk signals to neighboring muscle EMG in monopolar recording mode, but this proportion decreased with spatial filtering (50% and 42% for single and double differential, respectively). Crosstalk induced overestimations of intermuscular correlation and has a small effect on the EMG power spectrum, which indicates that crosstalk is not reduced with high-pass temporal filtering. Conversely, spatial filtering diminished the crosstalk magnitude and the overestimations of intermuscular correlation, confirming to be an effective and simple technique to reduce crosstalk. This paper presents a new method for the identification and quantification of crosstalk at the motor unit level and clarifies the influence of crosstalk on EMG interpretation for muscles with different anatomy
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